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Oreos lowering Blood Cholesterol, Science Communication, Mechanisms of Heart Disease, Ft. Dr. Norwitz, Dave Feldman

2024-03-1603:16:01

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live Sessions with Me, Consulting Lite, and More *JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST*One Weekly Email of Value: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H *DONATIONS FOR A SCIENCE BASED CAUSE*Patreon: https://bit.ly/PhysionicPatreon *OTHER SOCIAL MEDIA*Instagram: http://bit.ly/2OBFe7i Nick's Channel: https://youtu.be/yiq67wpUhIs?si=AAercNmT4OX6fk_z Dave's Channel: https://youtu.be/RzG6N8WWufM?si=XNl6HTJ66vUpZ0QT 0:00 - Introduction of Study 3:47 - Introduction to Dr. Nick Norwitz and Dave Feldman 8:31 - Dr. Norwitz details the Oreo Study 31:52 - Problems with Science Communication 1:12:42 - Discussion with Dave Feldman 1:15:20 - Lipid Heart Model of Heart Disease 1:27:28 - Lean Mass Hyper-Responders 1:35:10 - Mechanisms of Action Discussion

Dr. Brad Stanfield: A Discussion of Supplements for Longevity and Health

2023-12-1853:37

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT] *Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live Sessions with Me, Consulting Lite, and More *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* One Weekly Email of Value: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H *DONATIONS FOR A SCIENCE BASED CAUSE* Patreon: https://bit.ly/PhysionicPatreon *OTHER SOCIAL MEDIA* Instagram: http://bit.ly/2OBFe7i Dr. Stanfield's Channel: https://www.youtube.com/@DrBradStanfield Timestamps 0:00 – Introduction 1:05 – Nicotinamide Mononucleotide (NMN) 17:14 – Creatine 20:25 – Collagen Peptides 25:58 – Thoughts on Meta-Analyses 29:18 – Hyaluronic Acid 34:08 – Taurine 37:42 – Thoughts on Mouse Studies 39:55 – Do Blood Markers Matter for Longevity? 42:29 – Trusting Science/Experts 44:05 – Dr. Stanfield’s Motivations for Clinical Education 53:12 – Ending Remarks

Reconsidering Aging, Muscle Growth, Niacin Supplementation, Your Questions, and More

2023-11-1903:58:501

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Standard Tier]: https://bit.ly/PhysionicInsiders2 Join the Physionic Insiders [Pro Tier]: https://bit.ly/PhysionicInsidersPro *Standard Tier:* Access to the Premium Video Library, Full Study Analyses (+ Summaries), Insider Podcast, , Research Reviews, and More *Pro Tier:* All benefits of the Standard Tier + Live Sessions with Me, Consulting Lite, and More *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* One Weekly Email of Value: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H *DONATIONS FOR A SCIENCE BASED CAUSE* Patreon: https://bit.ly/PhysionicPatreon *OTHER SOCIAL MEDIA* Instagram: http://bit.ly/2OBFe7i 0:00 - Introduction 5:11 - How to think about Aging 33:48 - Oxidized Blood Lipoproteins 58:34 - Study shows Age Reversal 1:15:28 - Oxalates 1:28:28 - Creatine as a Nootropic 1:35:48 - Niacin and Heart Disease 2:13:17 - Methylene Blue 2:25:25 - NMN on Health 2:38:46 - Inflammation contributing to Heart Disease 2:50:39 - Understanding Cellular Energy for Muscle Growth 3:07:08 - Subscriber Questions & Comments 3:42:05 - Housekeeping

Carnivore Diet, LDL Cholesterol, Fasting & Inflammation, Taurine on Longevity, and much more...

2023-07-2803:03:00

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Table of Content 0:00 - Introduction 05:18 - Carnivore Diet 34:39 - LDL Cholesterol & Heart Disease 1:00:11 - Taurine on Longevity & Health 1:13:04 - One Meal a Day - Context Matters 1:22:27 - Fiber - Good or Bad? Mixed Reviews... 1:38:10 - Cancer is a Metabolic Disease? 2:07:10 - Fasting raises Inflammation!? 2:16:52 - Q&A 2:37:23 - Stories of Health Success 2:44:22 - My PhD Progress, Life outside of University

Insulin on Fat Loss, GlyNAC for Anti-Aging, The Physionic Dream.

2023-03-1802:46:162

JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H DONATIONS FOR A SCIENCE BASED CAUSE Patreon: patreon.com/PhysionicPhD WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 Podcast: http://bit.ly/2PThKz0 Instagram: http://bit.ly/2OBFe7i 0:00 – Introduction. 5:30 – Toxic Acrylamides in Coffee. 18:46 – The Physionic Dream. 50:05 – Sucralose and Insulin Sensitivity. 57:00 – Insulin & Body Fat. 1:23:25 – Carbohydrate-Insulin Model of Obesity. 2:17:35 – GlyNAC for Anti-Aging. 2:29:50 – Hyaluronic Acid on Skin Aging. 2:40:45 – The Future Content.

Removing my John Campbell Video, High Intensity Health, Sweeteners break your Fast?, and More.

2022-11-0501:21:41

JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 Podcast: http://bit.ly/2PThKz0 Instagram: http://bit.ly/2OBFe7i 0:00 - Introduction. 3:00 - Dr. John Campbell, High Intensity Health. 39:40 - Nutrition Gurus. 53:00 - My Investigation on Non-Nutritive Sweeteners. 1:03:05 - Improving the 'Detailed Study Analyses'. 1:09:53 - Sweeteners break your Fast? 1:14:23 - Alternate Day Fasting.

My High Blood Pressure Experience; Plastics impact on Insulin Resistance.

2022-06-2601:30:06

Hi, in this episode, I cover a bunch of topics from my experience at the doctor, my own hypocrisy, some things I learned from you, and finally - the main topic of discussion: Insulin resistance and how plastics (phthalates) affect it. Oh, and if you're on Spotify or YouTube, it's now a video podcast, as well! MY COURSES, INSIDERS COMMUNITY, & CONSULTING - Join the ‘Physionic Insiders’ (Exclusive Content): https://www.patreon.com/PhysionicPhD - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6

Issues with Nutrition Documentaries; Caffeine and Performance - They Don't Always Mix.

2022-05-2801:25:23

Hi folks, in this episode I unintentionally discussed two topics. One, I planned on discussing, which was caffeine and it's performance effects in weight lifting and endurance. However, because I woke myself up to a nutrition documentary that I watched for 20 minutes or so before recording, I felt I had to get some things off my chest related to the second topic - nutrition documentaries. So, you have the distinct pleasure (or dismay) of listening to me ramble on both, but I hope that either way you learn something of use, especially related to caffeine. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Video and Studies on Caffeine: https://youtu.be/9WTbwlU5yOs

Nutrition & Pharmaceutical Therapies: Fat related Cancers

2022-04-1401:26:52

In this episode, the first of a more relaxed, long form podcast style, we're going to dive into how fat relates to cancers - the mechanisms, but beyond that, the different therapies employed by pharmaceuticals, along with the use of nutrition to combat certain cancers. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Related Videos: Mechanisms: https://youtu.be/Ijt1lqxn2AQ Therapies: https://youtu.be/iLdcoIIiByo Scientific Review: Reprogramming of Fatty Acid Metabolism in Cancer British Journal of Cancer

Let's Change how We do Things Here.

2022-03-3114:21

I think you'd be better served if we change how we do things on the Physionic Podcast. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6

Carbohydrates slow Metabolism and Mitochondrial Breathing.

2022-03-2519:16

In this episode, I'm going to begin the explanation as to what effects carbohydrates have on our metabolism, and one potential effect in our mitochondria. Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs34%5D-a-high-carbohydrate-diet-lowers-the-rate-of-adipose-tissue-mitochondrial-respiration Video: https://www.youtube.com/watch?v=7uBHNUSI6hI Previous Video on Carbs and Metabolism: https://www.youtube.com/watch?v=xn8VJzGCK5U&t=2s MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Study: A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration Benjamin Bikman

An Exception to the Insulin Sensitivity Effects of Saturated Fat [Study 31]

2022-03-1828:45

In this episode, we'll discuss a potential exception to the negative results on insulin sensitivity we've been discussing with the exposure to saturated fat. Study, Notes, & Amendments: https://www.physionic.org/examine/%5B31%5D-palmitate-acutely-induces-insulin-resistance-in-isolated-muscle-from-obese-but-not-lean-humans Video: https://youtu.be/ldUBG4-EJDo MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Study: Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans. A Brianne Thrush

Mitochondria & Diabetes: How Nutrition Connects the Two. [Study 32]

2022-03-1029:43

Hi all, in this episode, I'm going to describe to you how your nutrition, generally, affects your mitochondria in diabetes specific cells and how long term habits in nutrition can lead to diabetes (type 2). Enjoy. Video Version: https://youtu.be/x6EOhTzVKsE Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-and-energy-expenditure MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Study: Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure Marc Liesa

Your Nutrition affects your Mitochondria (Fasting vs Overconsumption) [Study 32]

2022-03-0335:051

In this episode, we'll be diving into two ways your mitochondria change their "behavior" to the exposure to different nutrition situations (high vs low nutrient presence). Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-and-energy-expenditure Video: https://www.youtube.com/watch?v=KQBmtzT4VTU MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Study: Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure Marc Liesa

Saturated vs Unsaturated Fats: One is Worse for Insulin Resistance [Study 30]

2022-02-1842:32

In this episode, we'll be going over a new study that wanted to find out the effects a saturated fat heavy consumption would have on insulin resistance and signaling against an unsaturated fat heavy consumption. Video: https://youtu.be/QfII7CANt14 Study: https://www.physionic.org/examine/%5Bs30%5D-dietary-palmitate-and-oleate-differently-modulate-insulin-sensitivity-in-human-skeletal-muscle MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6 Sarabhai, T., Koliaki, C., Mastrototaro, L., Kahl, S., Pesta, D., Apostolopoulou, M., Wolkersdorfer, M., Bönner, A. C., Bobrov, P., Markgraf, D. F., Herder, C., & Roden, M. (2022). Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle. Diabetologia, 65(2), 301–314. https://doi.org/10.1007/s00125-021-05596-z

Unsaturated Fat to the Rescue: Insulin Signaling and Mitochondrial Health [Study 28]

2022-02-1044:56

In this episode, we continue our quest for understanding the effect saturated fats have on muscle insulin signaling and mitochondrial health - however, beyond that, we'll be looking at how unsaturated fats may protect against the deleterious effects of saturated fat? Let's see.. Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs28%5D-different-effects-of-oleate-vs.-palmitate-on-mitochondrial-function%2C-apoptosis%2C-and-insulin-signaling-in-l6-skeletal-muscle-cells%3A-role-of-oxidative-stress- Video: https://youtu.be/TiO16KoH0Fs Study Title: Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Larysa Yuzefovych

Saturated Fat - Friend or Foe for Insulin Sensitivity and Mitochondrial Function? [Study 27]

2022-02-0423:53

In this episode, I'm kicking off a new format that's more tailored to the podcast listeners, so there's less need to head to the video versions of the podcast to understand half of what I'm talking about. In this episode, we'll be discussing saturated fat (palmitate) and it's effects in relation to insulin signaling in muscle cells, as well as mitochondrial function. What are the effects? What are the implications? Video: https://youtu.be/zMkV91E2Bic Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249685/

Body Fat is lost from THIS - NOT HORMONES

2021-11-0441:58

In this episode, I attempt to make sense of calories in vs out and reconcile that with the hormone argument for fat loss. Video Podcast: https://youtu.be/x1ZjjDzCdc0 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6

THIS is how Mitochondria DESTROY your Cells.

2021-10-2822:18

Mitochondria have a dark side, find out how. Video Podcast: https://www.youtube.com/watch?v=HPx7cv1I7eU MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6

Long Term Effects from Fat Loss - Hormones, Weight Regain? [Study Breakdown]

2021-10-1438:21

In this podcast, we look at a study that investigates how weight loss affects hormones and long term weight regain - is the deck stacked against you? Study: https://www.nejm.org/doi/full/10.1056/nejmoa1105816 Video Podcast: https://youtu.be/-t5d0S5MRwE 0:00 - Introduction 2:47 - Study Design 6:58 - Weight Loss & Weight Regain Results 9:45 - Long Term Hormonal Changes from Weight Loss 34:12 - Conclusions/Take Aways MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly/2AXIzK6

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Jennifer Worth