1. Considerations with surgery, radiation, rate of relapse
2. Adjuvant chemotherapy
3. Adjuvant immune checkpoint inhibition
4. Emerging neoadjuvant trial

 Citations

As always, citations, and sources include education from our respective training programs, the Devita textbook, and Uptodate.com.  We highly encourage review of guidelines published by ASCO, ESMO and other organizations local to your practice.

DeVita, Vincent T., Jr., Theodore S. Lawrence, and Steven A. Rosenberg. Devita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 10th edition. Philadelphia: Wolters Kluwer, 2015.

Uptodate.com Waltham, MA: Wolters Kluwer.

Great summary of differences in 7th and 8th staging editions (misspoke in episode as radiopedia):

https://radiologyassistant.nl/chest/lung-cancer/tnm-classification-8th-edition

1.           Spicer J et al.  JCO. 2023;41(16_suppl):8521-8521. doi:10.1200/JCO.2023.41.16_SUPPL.8521

2.           Wakelee H et al. NEJM. Published online June 3, 2023. doi:10.1056/NEJMOA2302983

3.           Forde PM et al. NEJM. 2022;386(21):1973-1985. doi:10.1056/NEJMOA2202170

4.           Winton T et al. NEJM. 2005;352(25):2589-2597. doi:10.1056/NEJMOA043623

5.           Stewart et al. BMJ. 1995;311(7010):899-909. doi:10.1136/BMJ.311.7010.899

6.           Arriagada R et al. NEJM. 2004;350(4):351-360. doi:10.1056/NEJMOA031644

7.           Felip E et al. The Lancet. 2021;398(10308):1344-1357. doi:10.1016/S0140-6736(21)02098-5

8.           Strauss GM et al. J Clin Oncol. 2008;26(31):5043-5051. doi:10.1200/JCO.2008.16.4855

9.        Pignon JP et al. JCO. 2008;26(21):3552-3559. doi:10.1200/JCO.2007.13.9030

Disclosures

Talking about Tumors with Ryan and Ryann is not medical advice.  We have received no funding in relation to the information discussed within this episode and have no financial conflicts of interest to disclose.  All opinions are those of whoever stated them.  We have compiled this podcast to serve as an introduction to the field of medical oncology for post-graduate trainees interested in the topic. 

Tags

Hematology/Oncology, evidence based medicine, education, chemotherapy, immunotherapy, medical oncology