15.- Hugo Oliveira: phage depolymerases and Acinetobacter baumanii phages
Description
Today we speak with Hugo Oliveira, researcher in the Center of Biological Engineering in Braga, Portugal. We discussed how depolymerases work, how to identify them in your phages, how to isolate phages with more than one depo, and what could be the secret to a cocktail that works against Acinetobacter baumanii.
Enjoy the episode!
Episode chapters:
What is your research focus?
Why Acinetobacter as a target?
What are depolymerases?
Where are they located in the genome?
What are the enzymatic activities?
What is the main use of this depolymerases in a context of application?
Do the phages have several depolymerases?
How can we isolate a phage with several depolymerases?
How can we detect the depolymerases in the genome?
How did you start in the world of phages?
Do you have advice for people starting on the field?
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