17 – GLP-1 in Type 1 Diabetes: beyond weight loss, towards metabolic therapy?
Update: 2025-09-12
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Episode 17 — GLP-1 in Type 1 Diabetes: Beyond Weight Loss, Towards Metabolic Therapy
Go to the Podcast page for all the notes, insights, and further reading & listening.
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Guest: Professor Viral Shah, MD
- Professor of Medicine & Director of Diabetes Clinical Research, Center for Diabetes and Metabolic Diseases, IU School of Medicine
- Author of multiple clinical trials and consensus guidelines on GLP-1 and incretin therapies in type 1 diabetes
In this episode, John Pemberton speaks with Professor Viral Shah, a leading researcher in incretin therapies, about:
- The unique challenges of type 1 diabetes (insulin resistance, glucagon, weight gain).
- The evidence for GLP-1s in T1D: up to 30% insulin reduction, weight loss, and improved time in range.
- Practical guidance for people with type 1 and healthcare professionals: insulin titration, MDI vs pump vs AID, nutrition, and risk–benefit.
Subscribe to The Glucose Never Lies® and receive the Summary PDF with all the key take-home messages and practical implementation strategies.
Go to the Podcast page for all the notes, insights, and further reading & listening.
Related GNL Resources
- Overcoming Insulin Resistance in T1D
- Eight Causes of Insulin Resistance
- Seven Ways to Combat Insulin Resistance
- Automated Insulin Delivery Series
- CGM Series
- GNL Podcast Episode 14 Overcoming Insulin Resistance
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