343: Nucleotides to the Defense
Update: 2025-10-25
Description
TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides.
Hosts: Michael Schmidt and Mark O. Martin
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Links for this episode:
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Decoy cyclic nucleotides in phage defense (Nature)
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CRISPR defense with nucleotides (Nature)
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A decoy defence molecule to set a trap for viruses (Nature)
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Cyclic oligonucleotide-based antiphage signaling system immunity (Curr Opin Immunol)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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