49ers Face Depth Test in Colts Clash

49ers Face Depth Test in Colts Clash

Update: 2025-12-22
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49ers Face Key Injuries in Crucial Week Sixteen Matchup: The San Francisco 49ers are dealing with significant injuries ahead of their Monday night showdown against the Colts, with wide receiver Ricky Pearsall, cornerback Renardo Green, and rookie quarterback Kurtis Rourke all out. Pearsalls absence will shift offensive snaps to other receivers and running back Christian McCaffrey. Greens injury weakens the secondary, while Rourkes absence may impact the teams depth. However, linebacker Tatum Bethune and defensive lineman Sam Okuayinonu are set to play, and the team remains confident in their depth as they push for a playoff spot.

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49ers Face Depth Test in Colts Clash

49ers Face Depth Test in Colts Clash