Powerful women have always had to play the game a little differently than their male counterparts, but the story of Irene of Athens, who played politics with enough dexterity to become Empress of the Byzantine Empire for about 20 years in the 8th century, is extraordinarily complicated. The daughter of a prominent Greek family, she was brought to Constantinople as a possible bride for the future Emperor Leo IV. The marriage happened, a son was produced, but religious factionalism ultimately tore the marriage apart.

Upon Leo IV's death, Irene - as one would - stepped in as regent for their young son, the future Constantine VI. She outwitted Leo's half-brothers who were attempting to install the eldest to the throne by having them ordained as priests, and then took unusual steps to unify her kingdom's faith and pursue friendlier relations with the Carolingian empire in Europe.

New conflicts emerged when Constantine VI came of age, a situation that Irene met by undermining his rule and eventually ensuring he met an untimely and painful end. Irene was eventually deposed in 802 and was exiled to the Isle of Lesbos. She spent her final year spinning wool to support herself.

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