Assessing Recurrence Following Pulsed Field Ablation for Atrial Fibrillation

Guest: Nicholas Tan, M.D., M.S.

Host: Anthony H. Kashou, M.D.

Pulsed field ablation has been rapidly adopted across the United States since FDA approval was granted 1 year ago, due to its excellent acute efficacy, favorable safety profile, and fast workflow. However, recurrences post-ablation are comparable to that of previously established modalities, making this a significant hurdle that has yet to be overcome. Changes to mapping/ablation strategies, updates to PFA parameters, autonomic modulation, and combination modality ablations (PFA/RFA) offer some avenues for improvement

Topics Discussed:

•  What is pulsed field ablation (PFA) and how does it differ from previously established modalities of ablation such as radiofrequency and cryoablation?


• What are the recurrence rates post-PFA and how do they compare with other modalities?


• In patients who undergo redo ablations following an index PFA procedure, what are the most common causes (i.e. reconnection of pulmonary veins versus new sites)?


• How do you think PFA will evolve in the coming years

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Podcast episode transcript found here.