Bacterial chondronecrosis with osteomyelitis is one of the toughest puzzles in modern broiler production. In this episode of Unplucked, host Andy Vance sits down with Dr. Adnan Alrubaye of the University of Arkansas to explain why BCO lameness resists simple fixes and what the latest science says about preventing it. Dr. Alrubaye connects the dots between fast growth, microfractures in long bones, and the way a compromised gut can let bacteria slip into the bloodstream and settle where birds hurt most. He shares clear, barn-ready takeaways on managing gut integrity, spotting risk before it spikes late in the grow out, and why even small improvements in litter, ventilation, and nutrition can reduce both welfare concerns and condemnations.

The conversation moves from fundamentals to frontiers. Listeners get an accessible tour of next-generation tools, from rapid sequencing and microbiome profiling to early life interventions that aim to prime immunity before hatch. Dr. Alrubaye describes how precision microbiology is reshaping our understanding of the many organisms linked to BCO, why culture-based methods tell only part of the story, and how more innovative diagnostics can guide targeted feed additives and vaccination strategies. He also makes a strong economic case for prevention, reminding us that lameness often shows up when producers have the most invested in each bird.

Along the way, Andy and Dr. Alrubaye talk about the human side of progress. They highlight the role of mentorship and international collaboration in moving research from the lab bench to the broiler house, and they close with practical advice for students and early-career scientists on building resilience, finding good partners, and staying disciplined when the work gets hard. If you want a frank, hopeful roadmap for turning complex biology into better outcomes on the farm, this episode delivers both.

CREDITS

Host - Andy Vance

Producer - Lyndsey Johnson

Audio Editor & Engineer - Michael Lunt

LEGAL

The information provided in this episode of Unplucked is for informational and educational purposes only and should not be considered professional advice. While we discuss scientific research, public health, and industry practices, this podcast does not substitute for advice from qualified industry and scientific professionals. The views expressed in this episode are solely those of the host and guests and do not necessarily reflect the official opinions of The Poultry Science Association, their respective affiliates, or employees.