DiscoverBrain InspiredBI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas
BI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas

BI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas

Update: 2025-10-08
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Nikolay Kukushkin is an associate professor at New York University, and a senior scientist at Thomas Carew’s laboratory at the Center for Neural Science. He describes himself as a "molecular philosopher", owing to his day job as a molecular biologist and his broad perspective on how it "hangs together", in the words of Wilfrid Sellers, who in 1962 wrote, “The aim of philosophy, abstractly formulated, is to understand how things in the broadest possible sense of the term hang together in the broadest possible sense of the term”.





That is what Niko does in his book One Hand Clapping: Unraveling the Mystery of the Human Mind.





This book is about essences across spatial scales in nature. More precisely, it's about giving names to what is fundamental, or essential, to how things and processes function in nature. Niko argues those essences are where meaning resides. That's very abstract, and we'll spell it out more during the discussion. But as an example at the small scale, the essences of carbon and oxygen, respectively, are creation and destruction, which allows metabolism to occur in biological organisms. Moving way up the scale, following this essence perspective leads Niko to the conclusion that there is no separation between our minds and the world, and that instead we should embrace the relational aspect of mind and world as a unifying principle. On the way, via evolution, we discuss many more examples, plus some of his own work studying how memory works in individual cells, not just neurons or populations of neurons in brains.









Read the transcript.





0:00 - Intro
9:28 - Studying memory in cells
10:14 - Who the book is for
17:57 - Studying memory in cells
21:53 - What is memory?
29:49 - Book
29:52 - How the book came about
37:56 - Central message of the book
44:07 - Meaning in nature
49:09 - Meaning and essence
51:55 - Multicellularity and ant colonies
57:43 - Eukaryotes and complexification
1:03:38 - Why do we have brains?
1:06:17 - Emergence
1:10:58 - Language
1:12:41 - Human evolution
1:14:41 - Artificial intelligence, meaning and essences
1:25:49 - Consciousness

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BI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas

BI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas

Paul Middlebrooks