DiscoverThe Block M Podcast Network: A University of Michigan PodcastBest Week 5 bets for Oregon-Penn State, Georgia-Alabama, Ohio State-Washington, LSU-Ole Miss
Best Week 5 bets for Oregon-Penn State, Georgia-Alabama, Ohio State-Washington, LSU-Ole Miss

Best Week 5 bets for Oregon-Penn State, Georgia-Alabama, Ohio State-Washington, LSU-Ole Miss

Update: 2025-09-25
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Week 5 may be the best on paper of the college football season up to this point. Four Top-25 matchups are on deck this weekend, including a Top-10 game in Happy Valley between Penn State and Oregon. The Nittany Lions are favored by a little more than a field goal heading into the game, but the Ducks have looked impressive so far in the early portion of the season. Will James Franklin get the monkey off his back when it comes to big games, or will Dan Lanning remind Penn State which team won the Big Ten a season ago?


Von Lozon and Kellen Voss go against the spread for that game and all the best games that Week 5 has to offer in this week’s Pick’em Podcast!


All odds courtesy of DraftKings Sportsbook. Please gamble responsibly.


No. 24 TCU at Arizona State (-2.5)
No. 11 Indiana (-7.5) at Iowa
Arizona at Iowa State (-6.5)
No. 21 USC (-6.5) at No. 23 Illinois
No. 4 LSU at No. 13 Ole Miss (-2.5)
No. 1 Ohio State (-8.5) at Washington
No. 17 Alabama at No. 5 Georgia (-3)
No. 6 Oregon at No. 3 Penn State (-3.5)

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Best Week 5 bets for Oregon-Penn State, Georgia-Alabama, Ohio State-Washington, LSU-Ole Miss

Best Week 5 bets for Oregon-Penn State, Georgia-Alabama, Ohio State-Washington, LSU-Ole Miss

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