DiscoverEP EdgeBeyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5
Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5

Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5

Update: 2025-10-27
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In this episode of EP Edge Podcast, Dr. Niraj Sharma dives deep into the clinical promise and procedural realities of LBBAP:

  • Clinical advantages: improved LVEF, narrower QRS, lower VT/VF and AF incidence.
  • RV protection: reduced risk of pacing-induced cardiomyopathy.
  • Sex-specific outcomes: women with NICM + LBBB derive greater benefit.
  • Complications: lead fracture, TR progression, microperforations, and capture failure.
  • Future directions: integrating imaging, refining technique, and advancing lead technology

 This is where physiology meets precision—and where CRT is being redefined.

For: Source data/infographics see EPEDGE Newsletter on LinkedIn
For feedback, collaborations, or questions, email Dr. Niraj Sharma at epedgecast@gmail.com or connect on LinkedIn

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Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5

Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5

Niraj Sharma MD FACC FHRS