Big 12 Week 4 Preview and Picks Against the Spread
Update: 2025-09-18
Description
Week 4 of the Big 12 football season is here, and Pete Mundo from Heartland College Sports is breaking down every game on the schedule, along with picks against the spread for three matchups you don’t want to miss.
From key non-conference showdowns to the first signs of separation in league play, here’s your complete Big 12 Week 4 preview and predictions.
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