DiscoverScience (Video)CARTA: The Industrialized Gut Microbiome with Justin and Erica Sonnenburg
CARTA: The Industrialized Gut Microbiome with Justin and Erica Sonnenburg

CARTA: The Industrialized Gut Microbiome with Justin and Erica Sonnenburg

Update: 2025-06-27
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The human gut microbiome is tightly linked our health. Our analyses of diverse human populations from around the globe, ranging from hunter-gatherer to industrialized, show that the gut microbiome is profoundly influenced by lifestyle. With a large collaborative team, we conducted deep metagenomic sequencing of the gut microbiomes of Tsimane horticulturalists from Bolivia and compared them to those of Hadza hunter-gatherers from Tanzania. We are also investigating whether diet and microbial therapies can address deficiencies in the industrialized gut community. Molecular mechanisms of host-microbial interaction are pursued using an array of technologies and experimental approaches including gnotobiotic and conventional mouse models, quantitative imaging, and a metabolomics pipeline focused on investigating microbiota-dependent metabolites. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40698]
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CARTA: The Industrialized Gut Microbiome with Justin and Erica Sonnenburg

CARTA: The Industrialized Gut Microbiome with Justin and Erica Sonnenburg

UCTV: UC San Diego