Clemson vs. Louisville Pick 11/14/25 College Football Week 12 Pick Prediction
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Clemson vs. Louisville College Football Pick Prediction 11/14/2025 by Tony T.
Clemson at Louisville 7:30 PM ET— Clemson improved to 4-5 following their 24-10 home victory against Florida St. The Tigers had movement in their run game with 98 yards rushing for 2.7 yards a carry. On defense they allowed 4.2 yards per run with 250 yards passing for 5.8 yards per pass attempt. Cade Klubnik completed 20 of 27 for 221 yards and a touchdown. Louisville drops to 7-2 with their 29-26 home defeat to California. The Cardinals were inefficient through the air and rushed for 145 yards for 4.9 yards a carry. On defense they allowed 3.1 yards per run with 350 yards passing for 7.1 yards per pass attempt. Miller Moss hit 20 of 3 for 203 yards with an interception.
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