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Continuous or Intermittent B-Lactam Infusions for Sepsis?

Continuous or Intermittent B-Lactam Infusions for Sepsis?

Update: 2024-09-24

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Timely administration of broad-spectrum antibiotics is a critical pillar in the resuscitation of patients with sepsis. B-lactam antibiotics are an important class of antibiotics commonly administered to patients with sepsis. Typically, B-lactam antibiotics are administered over 30 minutes, but optimal bactericidal activity requires the concentration of free drug to be above the MIC of the organism for 40-70% of the dosing interval. In this podcast we discuss two recent publications that compare continuous infusions of B-lactam antibiotics with intermittent effusions in patients with sepsis.

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Continuous or Intermittent B-Lactam Infusions for Sepsis?

Continuous or Intermittent B-Lactam Infusions for Sepsis?

Critical Care Perspectives in Emergency Medicine