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Join us for a discussion about subclinical mastitis in dairy goats caused by non-aureus Staph species (NAS) with Dr. Michelle Buckley. This research was completed during her time as a post-doctoral associate at Iowa State University with support from the USDA National Institute of Food and Agriculture, Agricultural and Food Research Initiative Competitive Program, Mitigating Antimicrobial Resistance Across the Food Chain, Grant/Award Number: 2021-69015-33501. Dr. Buckley is currently an Assistant Professor of Clinical Practice at Texas Tech University: https://www.depts.ttu.edu/vetschool/about/meet-our-team/faculty/michelle-buckley/

In this episode we discuss two drugs that can be used in an extra-label manner to address subclinical mastitis in dairy goats during the dry period: Orbenin DC (cloxacillin benzathine) and ToMORROW (cephapirin benzathine). Dr. Buckley's work evaluated how long it took for both drugs to leave the goats' bodies after administration in both meat and milk as well as how effective they were at curing subclinical mastitis due to non-aureus Staph. She also evaluated antimicrobial resistance development due to treatment with these long-acting intramammary products.

The published work that we discuss is titled "Pharmacokinetics of long acting cephapirin and cloxacillin after intramammary administration in dairy goats" and it can be found in the Journal of Veterinary Pharmacology and Therapeutics here: https://onlinelibrary.wiley.com/doi/10.1111/jvp.13445

Additional publications will be added to the episode notes as they become available.

As part of this research, the Dairy Goat Extension and Education website was developed to provide veterinarians and producers with resources for ensuring antimicrobial stewardship and milk quality in dairy goats. This website includes short video training modules as well as electronic records templates and other useful resources: https://www.dairygoatextension.org/

As we mention several times during this episode, the drug use discussed here is extra-label and will require extended withdrawal recommendations to avoid violative residues in the food supply after use. Please contact the Food Animal Residue Avoidance Databank for guidance here: http://www.farad.org/

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