Dehua Pei: How Do Large Molecules Pass Through Cell Membranes?
Description
</figure>Dehua Pei, Distinguished Professor of Chemistry and Biochemistry, discusses his groundbreaking research on how biomolecules, particularly large proteins, traverse cell membranes. This fundamental question has significant implications for drug discovery. His team has identified a new mechanism they call vesicle budding and collapse (VBC) and is exploring its potential to deliver therapeutic agents for diseases like cancer and Alzheimer’s. Pei and host David Staley discuss the importance of combining curiosity-driven research with societal needs, aiming to solve “undruggable” diseases (those lacking drug treatments) and improve sustainable agriculture. He also describes his journey from doing fundamental research to founding four biotech companies.
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United States
