Lauren and JJ investigate a case of lethargy, inappetence, vomiting, and distended abdomen in a cat.

This episode is part 1 of 2.

This episode contains a detailed review of feline infectious peritonitis (FIP).

Resources:

• Rothrock, K., & Brister, J. (2024). Feline infectious peritonitis (feline). VINcyclopedia of Diseases. www.vin.com


• Coggins, S. J., et al. (2023). Outcomes of treatment of cats with feline infectious peritonitis using parenterally administered remdesivir, with or without transition to orally administered GS-441524. Journal of Veterinary Internal Medicine, 37(5), 1772-1783. https://onlinelibrary.wiley.com/doi/10.1111/jvim.16803


• Taylor, S. S., et al. (2023). Retrospective study and outcome of 307 cats with feline infectious peritonitis treated with legally sourced veterinary compounded preparations of remdesivir and GS-441524 (2020-2022). Journal of Feline Medicine and Surgery, 25(9). https://journals.sagepub.com/doi/full/10.1177/1098612X231194460


• Wogan, L. (2024). Confusion besets first legal FIP treatment in us (updated). VIN News Service. https://news.vin.com/default.aspx?pid=210&Id=11910939&sx=239128590&n=1&f5=1


• Wogan, L. (2024). Overdue good news arrives for FIP cats in the US. VIN News Service. https://news.vin.com/default.aspx?pid=210&Id=12090343&f5=1


• FIP Resources for Veterinarians. Stokes Pharmacy. Last accessed November 19, 2024. https://www.stokespharmacy.com/fip/veterinary-resources/


• Green, J., et al. (2023). Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524. Journal of Veterinary Internal Medicine, 37(5), 1784-1793. https://onlinelibrary.wiley.com/doi/10.1111/jvim.16804


• Murphy, B. G., et al. (2018). The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. Veterinary Microbiology, 219(0), 226-233. https://www.sciencedirect.com/science/article/pii/S0378113518301603?via%3Dihub


• Pedersen, N. C., et al. (2019). Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis. Journal of Feline Medicine and Surgery, 21(4), 271-281. https://journals.sagepub.com/doi/10.1177/1098612X19825701


• Kent, A. M., et al. (2024). Unlicensed antiviral products used for the at-home treatment of feline infectious peritonitis contain GS-441524 at significantly different amounts than advertised. Journal of the American Veterinary Medical Association, 262(4), 489-497. https://avmajournals.avma.org/view/journals/javma/262/4/javma.23.08.0466.xml


• Allinder, M., et al. (2024). Uroliths composed of antiviral compound GS-441524 in 2 cats undergoing treatment for feline infectious peritonitis. Journal of Veterinary Internal Medicine, 38(1), 370-374. https://onlinelibrary.wiley.com/doi/10.1111/jvim.16954


• United States Food and Drug Administration. (2024). FDA announces position on use of compounded GS-441524 to treat FIP. Last accessed November 19, 2024. https://www.fda.gov/animal-veterinary/cvm-updates/fda-announces-position-use-compounded-gs-441524-treat-fip