SOHO Insider myeloproliferative neoplasms podcast host Andrew Kuykendall, MD, associate member in the Department of Malignant Hematology at the Moffitt Cancer Center, and guest Aaron Gerds, MD, MS, an associate professor at the Cleveland Clinic, discuss anemia in myelofibrosis in a SOHO Insider podcast.

 “I put anemia near the top of the list, or at least an equal footing with spleen and symptoms,”  Dr. Gerds said. He also noted that 40% of myelofibrosis patients face anemia at diagnosis, with nearly all affected over time.

The pair also discuss causes of anemia in myelofibrosis, such as bone marrow failure and inflammation, which complicate treatment. Past therapies targeted spleen size, but drugs like luspatercept and pelabresib offer hope. “We’re fighting this war on two fronts,” Dr.Gerds said.

Listen to more podcast episodes.