Ep 33 - Max Marchione: Superpower, Hims, and the future of AI-powered medicine
Description
Thanks to our partner, Godel Terminal — a full trading terminal at 10% of the price of a Bloomberg! CLICK HERE to get 25% off your first month and lock in lifetime access for $80/mo.
In episode 33 of Hims House, hosts Jonathan Stern and Patrick Lester sit down with Max Marchione, founder of Superpower — a health tech startup reimagining preventive care through AI, advanced diagnostics, and personalized protocols. The conversation explores how healthcare might look if rebuilt from first principles today, why AI could become the true "front door" to care, and how Superpower is betting on a tech-first model. Max also shares candid thoughts on Hims' billion-dollar raise, its AI and international strategy, the potential of peptides, and what it takes to build a healthcare brand with cultural pull.
00:00 – The Godel Terminal
01:01 – Intro - Max Marchione & Superpower’s Mission
02:40 – Reimagining Healthcare from First Principles
04:16 – AI as the New Front Door to Care
07:18 – Lessons Learned: Superpower’s Evolving Strategy
17:24 – Branding in Healthcare: Sci-Fi vs. Friendly
23:29 – Long-Term Vision: Membership, Outcomes, and Impact
28:01 – Vertical Integration & Personalized Therapeutics
30:14 – Hims, AI, and the Commoditization of Care
32:52 – Global Expansion: Who Hims Might Acquire
38:48 – What Peptides Are and Why They Matter
42:45 – Legal Gray Zones
46:43 – Innovation in the UAE & Saudi Arabia
50:11 – Taking More Risks
52:43 – Final Reflections
Get full access to Hims House at himshouse.substack.com/subscribe
United States
