Dennis Mckenna has been conducting research in ethnopharmacology for over 40 years in places like the Amazon so it's no surprise he is one of the most interesting people to have a conversation with. We ask Dennis to explain what's happening in our brains when we take psychedelics and how they can heal mental health wounds. We also touch on his documentary film project - Biognosis, reminisce about pre-covid ayahuasca retreats in Peru and discuss how important it is to stay curious throughout our life.