Episode 12: A SPRINT Through HTN Trials
Description
In Episode 12, Dr. William Cushman, co-investigator of the 2015 SPRINT (Systolic Blood Pressure Intervention) Trial, joins us for a discussion all about hypertension trials, their long history, and what's ahead for research in this space. Too young to remember SPRINT or looking for a "CliffsNotes" of HTN trials? This episode's for you!
Here's a Renal Fellow Network post from 2017 with a link to a cheat sheet of hypertension clinical trial.
Nephrons: Matthew Sparks, Samira Farouk
Guests: William Cushman, Medical Director & Professor, Department of Preventive Medicine, University of Tennessee
Links from the Show:
00:41 : Systolic Blood Pressure Intervention Trial (2015)
02:17 : VA Cooperative Study (1967)
05:13 : ACCORD Study (2010)
06:30 : SPRINT MIND (2019)
08:40 : Framingham Heart Study (Started 1948)
11:27 : Attended vs. unattended blood pressure – learnings beyond SPRINT (2021)
14:03 : Systolic Hypertension in the Elderly Program Study (1989)
14:05 : Hypertension Detection & Follow Up Program (1979)
15:32 : JNC 8 Guidelines (2014)
16:01 AHA/ACC Guidelines (2017)
17:54 : Syst-Eur (Treatment of HTN in Patients > 60 y, 1998)
17:54 : HYVET (Treatment of HTN in Patients > 80 y, 2008)
18:01 : Syst-China (2000)
22:18 : AAFP HTN Guidelines (2022)
22:40 : KDIGO HTN Guidelines (2021)
25:37 : ALLHAT Study (2002)
32:22 : Secondary Prevention of Small Subcortical Strokes Trial (SPS3, 2013)
United States
