DiscoverPrimary Care UpdateEpisode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone
Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

Update: 2025-10-29
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This week, Gary, Kate, Mark and Henry discuss the optimal duration of anticoagulation after a provoked DVT, using low doses of mirtazapine or amitriptyline in adults with insomnia, whether a lower dose of semaglutide is still effective for weight loss, and adding aspirin for patients with coronary heart disease, a stent and who are also on a DOAC for another indication.

Links:

NICE Barrett Esophagus guideline: https://pubmed.ncbi.nlm.nih.gov/38553042/

Essential Evidence Plus: www.essentialevidenceplus.com

Duration of anticoagulation: https://pubmed.ncbi.nlm.nih.gov/40888734/

Mirtazapine or amitriptyline for insomnia: ttps://pubmed.ncbi.nlm.nih.gov/39814428/

Lower dose semaglutide for obesity: https://pubmed.ncbi.nlm.nih.gov/40934115/

Adding aspirin: N Engl J Med . 2025 Oct 23;393(16):1578-1588https://pubmed.ncbi.nlm.nih.gov/40888725/


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Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

Episode 192: anticoag duration, old drugs for insomnia, lower dose Ozempic, and aspirin + anticoag or anticoag alone

Mark Ebell