Just about a month ago, 9,600 researchers, clinicians, and representatives from patient advocacy organizations gathered in Barcelona for the European Committee on Treatment and Research in MS annual scientific congress, better known as ECTRIMS, the largest MS research conference in the world.

Now that he's had an opportunity to review his notes and digest all of the science presented at ECTRIMS 2025, Dr. Bruce Bebo, the National MS Society's Executive Vice-President of Research, returns to the podcast to take us on a deep dive covering some of the most important research presented this year.

We're also talking about next-generation CAR T-cell therapy for MS, and we'll explain why it's such exciting news.

We're sharing details about a DNA-based therapy for overactive bladder that just received fast-track status from the FDA.

We'll tell you about a new effort to develop a simple blood test that will detect MS progression.

We have some news to share about the RealTalk MS app. And we want to remind you to check out our ECTRIMS Extra Conversations video playlist on the RealTalk MS YouTube channel!

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: A deep dive into the research presented at ECTRIMS 2025  :22

Kernal Biologics received $48 million grant for the next-generation CAR T-Cell therapy  2:35

FDA grants fast track designation to DNA-based therapy to treat overactive bladder  6:02

Octave Bioscience receives grant to develop a blood test to detect MS progression  8:30

News about our app  9:42

Have you checked out our ECTRIMS Extra Conversations YouTube playlist?  10:30

Dr. Bruce Bebo discusses some of the most important research presented at ECTRIMS 2025  11:06

Share this episode  32:26

Next week's episode  32:47

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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

PARTICIPATE: Take the Shaping Tomorrow Together Survey
https://s.alchemer.com/s3/Perspectives-on-MS

REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA
https://nmss.quorum.us/event/25463

SIGN UP: Become an MS Activist
https://nationalmssociety.org/advocacy

LISTEN: RealTalk MS Ep 422: From ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug
https://realtalkms.com/422

WATCH: The RealTalk MS ECTRIMS Extra Conversations video playlist on YouTube
https://realtalkms.com/ectrims2025

JOIN: The RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

DOWNLOAD: The RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

DOWNLOAD: The RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

REVIEW: Give RealTalk MS a rating and review
http://www.realtalkms.com/review

Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 425
Guests: Dr. Bruce Bebo