Many of us know the feeling— after a night of having a few too many, you wake up feeling miserable. One of the great enigmas of our time, hangovers have been affecting humans for thousands of years. There must be a cure, right?

In this episode, we search for a hangover cure by talking with cocktail historian and Esquire staffwriter David Wondrich, Brown University professor Dr. Robert Swift, and Stephen Braun, author of "Buzz: the science and lore of alcohol and caffeine."