US equity futures lower with S&P down (1.4%). European equity markets are sharply lower, follows firmer close on Thursday. Asian equity markets were weaker. Bonds strengthen, tracking big move in treasuries which sees US 10-year at 3.95%. Dollar is weaker. Oil down. Gold extends to new record high. Industrial metals mixed. Bitcoin lower. Markets have been keying off renewed turbulence in US regional banking space after KRX fell 6% to four-month low amid regional-bank credit concerns, which added to concerns over souring loans following collapse of subprime auto lender Tricolor and autoparts maker First Brands. Developments drew attention to JP Morgan CEO Jamie Dimon's warning about potential for more revelations. Press also highlighted concerns stemming from riskier credit as big investors dial back exposure.

Companies Mentioned: CME Group, Eli Lilly, Novo Nordisk