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From Stress to Healing: Understanding the Biology of Trauma with Dr. Aimie Apigian

From Stress to Healing: Understanding the Biology of Trauma with Dr. Aimie Apigian

Update: 2025-10-03
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This episode of the Dr. K Show features a compelling conversation between Dr. Michael Karlfeldt and Dr. Aimie Apigian, focusing on the intricate relationship between stress, trauma, and overall health. Dr. Apigian, who recently launched a book on the biology of trauma, shares her personal journey of confusion between stress and trauma, which led to burnout and health issues. She emphasizes the importance of distinguishing between these two states, as understanding the difference is crucial for effective health management and recovery. 

The discussion delves into the physiological and psychological mechanisms that differentiate stress from trauma. Dr. Apigian outlines the five steps the body undergoes during a trauma response, explaining that stress is just one component of this process. She uses real-life examples, such as a veteran’s muscle injury and the experience of receiving a cancer diagnosis, to illustrate how the body and mind react to perceived threats. These responses can lead to feelings of powerlessness, shifts in metabolism, and the adoption of various survival strategies. A significant portion of the episode is dedicated to the cellular and metabolic changes that occur during trauma. 

Dr. Apigian explains the concept of the cell danger response, where the body conserves energy, leading to symptoms like heaviness and depression. The conversation highlights how unresolved trauma can accumulate over time, increasing the risk of chronic diseases and impacting both physical and emotional well-being. The role of the immune system and mitochondria in these processes is also discussed, underscoring the biological complexity of trauma. The impact of early life experiences and attachment on trauma responses is another key theme. Dr. Apigian discusses how past experiences and deeply held beliefs shape an individual’s perception of danger and influence their physiological reactions. Addressing these early influences is presented as essential for resolving trauma and improving long-term health outcomes. The episode also introduces an assessment tool for measuring trauma burden and stresses the importance of focusing on the impact of trauma rather than specific events. In conclusion, the conversation underscores the necessity of a safe and supportive environment for trauma therapy. 

Dr. Apigian compares trauma therapy to surgery, emphasizing the need for stabilization before addressing deep-seated issues. She highlights the importance of agency, self-efficacy, and the development of skills and resources to manage trauma. The episode wraps up with recommendations for further reading and resources, encouraging listeners to explore Dr. Apigian's book and continue their journey toward self-discovery and healing.

  • Dr. Michael Karlfeldt and Dr. Aimie Apigian discuss the critical differences between stress and trauma, emphasizing how unresolved trauma can lead to chronic health issues.
  • Dr. Apigian explains the physiological and psychological processes that occur during a trauma response, including the concept of the cell danger response.
  • Real-life examples, such as a veteran’s injury and receiving a cancer diagnosis, are used to illustrate how the body and mind react to trauma.
  • The conversation highlights the impact of early life experiences and attachment on an individual’s trauma response and long-term health.
  • The importance of a safe, supportive environment and proper stabilization before trauma therapy is stressed as essential for effective healing and recovery.

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From Stress to Healing: Understanding the Biology of Trauma with Dr. Aimie Apigian

From Stress to Healing: Understanding the Biology of Trauma with Dr. Aimie Apigian

Dr. Michael Karlfeldt