In this journal club webinar, Dr. Theofanis Liatis discusses his most recent publication on generalised tremors in dogs based on a collection of 198 cases. The objective of the research was to describe the clinical characteristics of the cases, the prevalence of the diseases associated with generalized tremors in dogs, and identify clinical features that could be associated with the underlying disease. A tremor is an involuntary, rhythmic, oscillatory movement of a body part and generalized tremors affect the entire body. However, these tremors may have different features, such as being activated upon gravity (postural) or deteriorating with excitement and movement (action‐related kinetic), being episodic or continuous, or accompanied by intention head tremors. Generalized tremors have been associated with idiopathic generalized tremor syndrome, mycotoxin intoxication as well as other toxic diseases (e.g., metaldehyde, avermectins), metabolic diseases (e.g., hypercalcemia, hypocalcemia, hyperphosphatemia, hyperchloremia, hypokalemia, hyperammonemia, hepatic encephalopathy), orthostatic tremors and hypomyelination or dysmyelination.