Genetic Risk for Aortic Aneurysm and Dissection
Update: 2025-05-01
Description

Heritability has long been known to play a role in aortic aneurysm and dissection for individuals with the Marfan and Loeys-Dietz syndromes. Recent research at Penn Medicine and elsewhere has revealed the presence of genetic variants linked to these syndromes in non-syndromic disease. In this podcast, clinical genetics specialist Staci Kallish, DO, discusses this phenomenon, reviews ongoing studies to determine the risk for aortic aneurysm and dissection in the general population, and the protocols for candidates for genetic evaluation and testing in at- risk populations.
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