DiscoverWealthing PodcastGlobal Innovation by Design: Leesa Soulodre on Venture Capital, Trust, and the Power of the Long Game Ep. 44
Global Innovation by Design: Leesa Soulodre on Venture Capital, Trust, and the Power of the Long Game Ep. 44

Global Innovation by Design: Leesa Soulodre on Venture Capital, Trust, and the Power of the Long Game Ep. 44

Update: 2025-12-18
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This week on the Wealthing Podcast, Alicia Castillo Holley is joined by Leesa Soulodre for a wide-ranging conversation on global entrepreneurship, venture capital, and the long game of building value with intention. 

Leesa shares her entrepreneurial journey and her current work across Luxembourg's innovation ecosystem, including her involvement with the Luxembourg Innovation Agency and the Luxembourg Supercomputing Center, offering a window into how public-private collaboration can fuel cutting-edge innovation. Leesa discusses her company's global expansion and the success of its fund, highlighting the Planet 43 program and the growth in portfolio value achieved through disciplined strategy and long-term vision. 

Together, Alicia and Leesa explore core themes in venture capital: from market positioning and ethical considerations to the importance of trust, alignment, and enduring relationships between founders and investors. Grounded in personal experiences, the conversation reflects on the real challenges and opportunities within the startup ecosystem and what it takes to build companies and partnerships that last.

About Leesa: Leesa Soulodre is Managing Partner of R3i Capital and Planet43, and Founder of the R3i Future Intelligence Lab. Through R3i, she has deployed capital across deep tech sectors including AI governance, climate resilience, healthcare, quantum computing, and water intelligence, guiding hundreds of corporations and funding more than 350 startups globally.

At the core of her work is the Future Intelligence Lab, a proprietary intelligence platform designed to capture regulatory alpha at scale amid the €130 trillion global regulatory repricing. Using its ES-RAS™ framework, the Lab has analyzed over 119,000 companies, built a 250TB proprietary dataset, generated 1,000+ IP assets, and launched multiple spinouts across healthcare, regtech, fintech, and space. 

Previously, Soulodre helped embed ESG and risk intelligence into 200+ institutional portfolios through advisory roles at RepRisk and GMI Ratings, shaping how global capital is allocated. Today, she serves on investment committees and boards across the U.S., Europe, Asia, and Australia, teaches at leading business schools, and contributes to global AI and governance standards. A TRIUM Global Executive MBA graduate, she is building a multi-generational venture platform with a $1B deployment vision—proving that systematic intelligence, breakthrough technology, and real-world impact belong together.

Connect with Leesa: https://www.linkedin.com/in/leesasoulodre/

🌐 Wealthing Club: wealthing.club

 

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Global Innovation by Design: Leesa Soulodre on Venture Capital, Trust, and the Power of the Long Game Ep. 44

Global Innovation by Design: Leesa Soulodre on Venture Capital, Trust, and the Power of the Long Game Ep. 44

Alicia Castillo Holley