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HER2-Altered Non-Small Cell Lung Cancer — An Interview with Dr John V Heymach

HER2-Altered Non-Small Cell Lung Cancer — An Interview with Dr John V Heymach

Update: 2025-12-10
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Featuring an interview with Dr John V Heymach, including the following topics:

  • Differentiating factors among various HER2 alterations in non-small cell lung cancer (NSCLC) (0:00 )
  • Activity of targeted agents across HER2 alterations in NSCLC (4:06 )
  • Available data with zongertinib and sevabertinib for HER2-mutant NSCLC (20:39 )
  • Case: A man in his late 40s with HER2-mutant NSCLC receives multiple lines of therapy, including trastuzumab deruxtecan (T-DXd) and zongertinib (29:23 )
  • Case: A woman in her mid 50s with HER2-mutant NSCLC receives zongertinib with durable response (34:23 )
  • Case: A woman in her late 50s with HER2-mutant NSCLC receives multiple lines of therapy, including sevabertinib and T-DXd (39:53 )
  • Investigational approaches in HER2-mutant NSCLC (46:31 )

CME information and select publications

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HER2-Altered Non-Small Cell Lung Cancer — An Interview with Dr John V Heymach

HER2-Altered Non-Small Cell Lung Cancer — An Interview with Dr John V Heymach

Dr. Neil Love