A randomized, double-blind, placebo-controlled trial investigated the sleep-promoting effects of Heukharang lettuce (Lactuca sativa L.) extract in Korean adults aged 30-65 with poor sleep quality (Pittsburgh Sleep Quality Index (PSQI) score > 5). Over four weeks, participants received two capsules daily of either the test extract or a placebo. The study found that the test group showed a greater improvement in global PSQI scores compared to the placebo group (6.48 ± 0.63 vs. 7.41 ± 0.57, p=0.0462). Objective measurements from actigraphy revealed significant improvements in total sleep time (TST) (421.68 ± 13.29 min vs. 386.57 ± 12.27 min, p=0.0023) and sleep efficiency (SE) (83.90 ± 1.60% vs. 81.01 ± 1.50%, p=0.0342) in the test group. Polysomnography (PSG) results also favored the test group, demonstrating higher TST (358.90 ± 19.75 min vs. 322.11 ± 17.66 min, p=0.0457), higher SE (86.86 ± 3.31% vs. 79.60 ± 2.99%, p=0.0182), and lower wake after sleep onset (WASO) (39.26 ± 10.57 min vs. 68.15 ± 9.60 min, p=0.0042). These findings suggest that Heukharang extract can enhance both sleep quality and quantity and is considered safe, indicating its potential as a functional food for improving sleep.

3. Disclaimers:

• This information is for educational purposes only and should not be interpreted as medical advice.

• The study discussed was conducted on Korean adults aged 30-65 with poor sleep quality. Further research may be needed to confirm these findings in other populations.

• Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.

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• (Remember to include a verbal disclaimer in the video itself.)

#LettuceSleep #HeukharangExtract #SleepQualityImprovement #SleepResearch #FunctionalFood

Son K, Lee M, Bok MK, Hwang KJ, Lim H. Sleep Promoting Effects of Lettuce (Lactuca sativa L.) Extracts in Korean Adults with Poor Sleep Quality: A Randomized, Double-Blind Placebo-Controlled Trial. Nutrients. 2025; 17(13):2172. https://doi.org/10.3390/nu17132172

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