DiscoverTrauma Bay PodcastHigh Dose Nitro for SCAPE and Sedation Discussion with Robert Mokszyscki PharmD, BCPS
High Dose Nitro for SCAPE and Sedation Discussion with Robert Mokszyscki PharmD, BCPS

High Dose Nitro for SCAPE and Sedation Discussion with Robert Mokszyscki PharmD, BCPS

Update: 2025-09-28
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In this episode we welcome our first guest Rob Mokszyscki PharmD, BCPS to the podcast. We discuss high dose Nitroglycerin for SCAPE, and also have a brief discussion on sedation agents.

Agrawal, N., Kumar, A., Aggarwal, P., & Jamshed, N. (2016). Sympathetic crashing acute pulmonary edema. Indian Journal of Critical Care Medicine, 20(12), 719–723. https://doi.org/10.4103/0972-5229.195710

Ashok, H., Shtembari, J., Achhami, E., Gaire, S., Shrestha, D. B., & Joshi, T. (2022). Valvular heart disease presenting as Sympathetic Crashing Acute Pulmonary Edema (SCAPE) phenomenon: A diagnostic and management paradigm. Cureus, 14(12), e32352. https://doi.org/10.7759/cureus.32352

Kelly, R. P., Gibbs, H. H., O’Rourke, M. F., Daley, J. E., Mang, K., Morgan, J. J., & Avolio, A. P. (1990). Nitroglycerin has more favourable effects on left ventricular afterload than apparent from measurement of pressure in a peripheral artery. European Heart Journal, 11(2), 138–144. https://doi.org/10.1093/oxfordjournals.eurheartj.a059669

Long, B., Brady, W. J., & Gottlieb, M. (2025). Emergency medicine updates: Sympathetic crashing acute pulmonary edema. The American Journal of Emergency Medicine, 90, 35–40. https://doi.org/10.1016/j.ajem.2024.12.061

Wilson, S. S., Kwiatkowski, G. M., Millis, S. R., Purakal, J. D., Mahajan, A. P., & Levy, P. D. (2017). Use of nitroglycerin by bolus prevents intensive care unit admission in patients with acute hypertensive heart failure. American Journal of Emergency Medicine, 35(1), 126–131. https://doi.org/10.1016/j.ajem.2016.10.038

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High Dose Nitro for SCAPE and Sedation Discussion with Robert Mokszyscki PharmD, BCPS

High Dose Nitro for SCAPE and Sedation Discussion with Robert Mokszyscki PharmD, BCPS

Max Hastings CEN, CCRN