DiscoverScience on Player FMHow Alphafold Has Changed Biology Research, 5 Years On - Science Friday
How Alphafold Has Changed Biology Research, 5 Years On - Science Friday

How Alphafold Has Changed Biology Research, 5 Years On - Science Friday

Update: 2025-11-18
Share

Description

Proteins are crucial for life. They're made of amino acids that “fold” into millions of different shapes. And depending on their structure, they do radically different things in our cells. For a long time, predicting those shapes for research was considered a grand biological challenge.

But in 2020, Google’s AI lab DeepMind released Alphafold, a tool that was able to accurately predict many of the structures necessary for understanding biological mechanisms in a matter of minutes. In 2024, the Alphafold team was awarded a Nobel Prize in chemistry for the advance.

Five years later after its release, Host Ira Flatow checks in on the state of that tech and how it’s being used in health research with John Jumper, one of the lead scientists responsible for developing Alphafold.

Guest: John Jumper, scientist at Google Deepmind and co-recipient of the 2024 Nobel Prize in chemistry.

Transcripts for each episode are available within 1-3 days at sciencefriday.com.


Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Comments 
loading
In Channel
loading
00:00
00:00
1.0x

0.5x

0.8x

1.0x

1.25x

1.5x

2.0x

3.0x

Sleep Timer

Off

End of Episode

5 Minutes

10 Minutes

15 Minutes

30 Minutes

45 Minutes

60 Minutes

120 Minutes

How Alphafold Has Changed Biology Research, 5 Years On - Science Friday

How Alphafold Has Changed Biology Research, 5 Years On - Science Friday