Welcome, everyone! 

This is Ralph Sanchez, and I am so pleased to bring you episode #6 to you here at the Alzheimer's Solution Revolution Channel. 

I am very much looking forward to today's topic, which is centered on the assessment of risk biomarkers for late-onset Alzheimer's disease. 

I'll begin this overview with a question.

Has your physician ever advised you on the possibility that you might be at an increased risk for dementia or late-onset Alzheimer's disease (LOAD)?

And in the regard, just how early in life is it prudent to begin the process of a personalized risk evaluation?

In fact, there has been a significant shift in the medical and research community mindset over the last 10 years, and the consensus is that midlife, or earlier, is a critical window of time to begin doing so.

Why? 

By midlife the brain damage associated with LOAD begins to hit a pivotal crisis point in terms of your risk for LOAD later in life—particularly if you are more susceptible to the disease.

 Now, I've talked about this in my book, articles, newsletters, and social media posts many times as Alzheimer's disease has a lengthy time frame of development and progression.

Indeed, the prevailing wisdom over these last few years has been finally emerged that the course of LOAD has a timeline of 20 to 30 years or so in which the disease process progresses.

And bear in mind, it is a silent disorder in the asymptomatic stage of LOAD—the preclinical stage, which might have its roots in cardiometabolic disease (type 2 diabetes/cardiovascular disease).

So today, I’ll be giving you some vital information on recent research findings that showcases what I just covered regarding your potential risk for LOAD, and how you can manage your healthy aging and reduce your risk for dementia through the assessment of biomarkers. 

Case in point, the findings of a recently published study—The  Offspring Study— of the Framingham Heart Study, revealed that: “These findings show for the first time that cardiovascular risk factors, including HDL which has not been consistently reported as a strong risk factor in Alzheimer's disease, contribute to the risk of Alzheimer's disease starting as early as age 35.” (Dr. Zhang)

Undoubtedly, if you have a family history of cardiometabolic disease, or dementia, it is critical to start looking at these risk factors earlier in life.

The pathology linked to the late-onset Alzheimer's disease continuum and vascular dementia spans decades, and it can be arrested or reversed in the early stages of the disease process.

Think ahead, and please listen to the podcast to get the rest of the story!

Ralph Sanchez, MTCM, CNS, D.Hom.

BrainDefend®

www.TheAlzheimersSolution.com

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