How Phage Therapy is Scaling to Meet Antibiotic Resistance with Jessica Sacher
Update: 2025-04-30
Description
Phage therapy is stepping into the spotlight as antibiotic resistance rises - and Jessica Sacher is helping lead the charge. In this episode, Ross Katz speaks with Jessica, Co-Founder of Phage Directory and Staff Scientist at Stanford, about sourcing phages, operationalizing therapy, and predicting efficacy through data. This conversation explores how personalized phage therapy works, its scalability, and the data challenges shaping its future.
What You'll Learn in This Episode:
- Why phage therapy is a promising solution to antibiotic-resistant infections
- How Phage Directory connects researchers and clinicians to accelerate treatment
- What operational hurdles exist in scaling personalized phage production
- How data science is being applied to predict effective phage-bacteria matches
- Why building infrastructure and awareness is essential to adoption in clinical care
Connect with Our Guest:
- Sponsor: CorrDyn, a data consultancy
- Find out more about Phage Directory
- Connect with Jessica on LinkedIn
Connect with Us:
- Follow the podcast for more insightful discussions on the latest in biotech and data science.
- Subscribe and leave a review if you enjoyed this episode!
Resources Mentioned:
- Why Language Itself Might Be Holding Back AI – by Ross Katz: https://www.linkedin.com/pulse/why-language-itself-might-holding-back-ai-ross-katz-rcl9e/?trackingId=Y6%2FH45W%2BxImfl%2By2geB6%2Bg%3D%3D
- Bacteriophage Therapy for Multidrug-Resistant Infections – PubMed: https://pubmed.ncbi.nlm.nih.gov/40026251/
- Cystic Fibrosis Australia and Phage Australia Survey – medRxiv: https://www.medrxiv.org/content/10.1101/2024.05.14.24307275v1
- Phage Directory: https://phage.directory/
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