Why are zebrafish so valuable to medical research? Find out how this tropical marvel is helping us learn more about neurological diseases. 

Explore the Uncommon Connections series to hear unusual stories behind some of history’s greatest medical breakthroughs and learn how uncommon connections between unexplained symptoms can lead to surprising diagnoses in rare diseases.

Visit the episode website for full notes, including references and legal information, or visit the Uncommon Connections channel on Omny.fm to listen to this episode and more. 

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References:

1. Bassett DI and Currie PD. The zebrafish as a model for muscular dystrophy and congenital myopathy. Hum Mol Genet 2003; 12: R265–R270.


2. Heath J. Animals in research: zebrafish. The Conversation. 2013 [cited 6 October 2021]. Available from: https://theconversation.com/animals-in-research-zebrafish-13804


3. Hill AJ et al. Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol Sci 2005; 86(1): 6–19.


4. Houart C. Zebrafish as an experimental organism. eLS 2001; 1–5.


5. Tucker E. How the zebra fish earned its stripes. Cascade. 2011 [cited 6 October 2021]. Available from: https://cascade.uoregon.edu/spring2011/features/feature2/how-the-zebrafish/index.html


6. Veldman MB and Lin S. Zebrafish as a developmental model organism for pediatric research. Pediatr Res 2008; 64(5): 470–6.


7. Widrick JJ et al. Discovery of Novel Therapeutics for Muscular Dystrophies using Zebrafish Phenotypic Screens. J Neuromuscul Dis 2019; 6(3): 271–7.

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MAT-AU-2102037. Date of preparation: November 2022. 2200475.

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