DiscoverThe Dr. Geo Prostate PodcastHow the Immune System Fights Prostate Cancer with Dr. Matthew Halpert, Phd
How the Immune System Fights Prostate Cancer with Dr. Matthew Halpert, Phd

How the Immune System Fights Prostate Cancer with Dr. Matthew Halpert, Phd

Update: 2025-10-25
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Description

Dr. Geo speaks with cancer immunologist Matthew Halpert, PhD about Immunocine, a dendritic-cell platform that “double-loads” patient-specific tumor signals to trigger a strong, physiologic immune response. Discussion includes mechanism, prostate cancer cases, how it can complement ADT and focal radiation, eligibility, workflow, and access.

Chapters

00:00 How the Immune System Fights Prostate Cancer

02:00 Why dendritic cells matter; generals vs NK/T “soldiers”

07:00 The “double-loading” breakthrough and fail-safe concept

14:00 Trials in difficult cancers; safety and early signals

18:00 Prostate cases: CRPC responses; lesions regressing

22:00 Combining with ADT and focal radiation; timing

27:00 Critical need for viable tissue; preservation tips

34:00 Patient journey: review → tissue + apheresis → 3 doses/6 weeks

41:00 Peri-lymphatic delivery; what patients feel; follow-up/boosts

49:00 Cost, access, insurance help; foundations; closing takeaways

Key Takeaways

  • Dendritic cells orchestrate immunity; NK/T cells execute.
  • Precision double-loading overcomes a built-in fail-safe to amplify activation.
  • Tissue access and preservation are essential for a broad, personalized target set.
  • Pragmatic combination care: ADT and selective radiation can create a therapeutic window and enhance antigen presentation.

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#DrGeoProstatePodcast #ProstateCancer #ProstateHealth #MensHealth #IntegrativeUrology #SBRT #Oligometastatic #RadiationOncology #PSMAPET #ADT


⚠️ Disclaimer

This episode is for educational purposes only and not medical advice. Always consult with a qualified healthcare provider. Geovanni Espinosa, N.D., assumes no liability for outcomes based on this content.


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How the Immune System Fights Prostate Cancer with Dr. Matthew Halpert, Phd

How the Immune System Fights Prostate Cancer with Dr. Matthew Halpert, Phd