DiscoverThe Brain PodcastIntrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis
Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis

Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis

Update: 2023-02-23
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Welcome to the 10th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.

In this episode we speak with Hideaki Nishihara and Britta Engelhardt, lead authors of the article entitled: Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis

This was a transcontinental recording with our guests dialing in from Japan and Europe. The article explores blood-brain barrier dysfunction as a pathogenic process of multiple sclerosis. The authors discuss the use of a novel in vitro model of the blood-brain barrier which was designed to capture the activity of adhesion molecules involved in leukocyte trafficking. 

Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac019

This episode was co-hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

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Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis

Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis