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LUNA3: Rilzabrutinib for ITP

LUNA3: Rilzabrutinib for ITP

Update: 2025-07-06
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Description

In this episode of Don't Just Read the Abstract, Pip and Rich critically appraise LUNA3, a 2:1 randomised controlled trial of rilzabrutinib vs placebo in adults with persistent or chronic ITP. This is the first therapy to prove an improvement in fatigue in ITP, but does it live up to expectation? Listen to this episode and find out.


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References


  1. Kuter et al. 2025 - LUNA-3 Trial
  2. Quality of Life Outcomes in Luna-3 (ASH Poster)


HaemSTAR is an independent UK-wide network of registrars in clinical haematology, interested in promoting and performing research in classical haematology. Our focus is on collaborative projects across haemostasis & thrombosis, transfusion, general haematology, and obstetric haematology.


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LUNA3: Rilzabrutinib for ITP

LUNA3: Rilzabrutinib for ITP