We continue to discuss a recent study that examines the role of Myeloid-derived Suppressor Cells in cancer and the expression of a receptor, DR-5, as a way to target these cells.

Article: Condamine T, Kumar V, Ramachandran IR, et al. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest. 2014;124(6):2626-2639. doi:10.1172/JCI74056 ⁠https://pubmed.ncbi.nlm.nih.gov/24789911/