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Management of Atopic Dermatitis with JAK Inhibitors: A Pediatric to Geriatric Perspective

Management of Atopic Dermatitis with JAK Inhibitors: A Pediatric to Geriatric Perspective

Update: 2025-10-02
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The recent expansion of the topical ruxolitinib approval to include pediatric patients aged 2 to 11 years with atopic dermatitis (AD) provides the first JAK inhibitor therapy option for this young population. In this episode, "Management of Atopic Dermatitis with JAK Inhibitors: A Pediatric to Geriatric Perspective," expert dermatologists, Christopher Bunick, MD, PhD and Karan Lal, DO discuss:

  1. Importance of JAK/STAT signaling in AD and the role of JAK inhibition in the future of dermatology

  2. Long-term safety of topical therapies for chronic AD

  3. Topline efficacy safety data from the phase 3 TRuE-AD3 clinical trial

  4. Shifting the paradigm of topical AD care across patient populations

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Management of Atopic Dermatitis with JAK Inhibitors: A Pediatric to Geriatric Perspective

Management of Atopic Dermatitis with JAK Inhibitors: A Pediatric to Geriatric Perspective