For those who have trouble going gently into that good night, sleep aids like ear plugs, white noise machines and weighted blankets are well-known tools in any veteran insomniac’s arsenal. Melatonin supplements are also popular — and might have a cardiac cost associated with them.

New research from the American Heart Association suggests long-term use for more than a year is associated with a “dramatic” increase of heart failure and death when compared with not using it.

The preliminary study also noted they were more likely to be hospitalized for heart failure, and to die from any cause.

Typically, the synthetic hormone is intended to mimic the body’s “version” of melatonin, which is responsible for curating your organic desire to wake up and/or go to sleep. In most cases, it’s intended for those who are experiencing difficulty falling asleep or combatting jet lag.

Notably, melatonin tablets are not regulated across the country, which can result in differences in quality and dosage.

In the study, researchers analyzed data from more than 130,000 adults. Among participants with insomnia, those whose data indicated long-term melatonin use of a year or more had about a 90% higher chance of a new heart failure diagnosis over five years compared with matched non-users.

While the study can only point to the possibility of a link between heart failure and extended melatonin usage, it should not be taken as cause — but study researchers say they plan on continuining to examine the safety of the sleep supplement on the heart, and how it can be used safely.

After all, most people are interested in counting sheep — not hospital visits.