Mitochondria & Metobolic Health: The Zone 2 Longevity Connection with Paul Laursen
Description
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In this episode of Stronger With Time, Dr. Tony Boutagy sits down with Professor Paul Laursen (renowned exercise physiologist, HIIT researcher, and co-founder of Athletica.ai) to discuss all things endurance training, zone 2 work, HIIT, fasted cardio and some of the misinformation around these training modalities.Â
In this Eposide:
00:00 â Intro: Why this conversation matters for women and coaches Â
01:00 â Paulâs background & why elite athletes arenât always healthy Â
03:00 â Metabolic dysfunction & burnout in high performers Â
06:00 â Muscle mass, mitochondria & why resistance alone isnât enough Â
08:00 â What Zone 2 actually does for your metabolic health Â
11:00 â How to test aerobic fitness without a lab (180-age method)Â Â
14:00 â Why building fat-burning capacity is so critical for women Â
17:00 â How many hours of Zone 2 do you really need? Â
19:00 â Why Zone 3 is âno manâs landâ & how to avoid overtraining Â
22:00 â Full breakdown of zone training (Zone 1â6 explained)Â Â
25:00 â When Zone 3 is usefulâand when itâs a mistake Â
26:00 â The science behind short intervals vs long ones Â
29:00 â Why 30/30 intervals work (and how to dose them properly)Â Â
33:00 â The biggest mistake most people make with intervals Â
35:00 â How much VOâmax training is enough for health & longevity Â
39:00 â Why base training *must* come before HIITÂ Â
41:00 â Do women respond differently to aerobic training? Â
44:00 â The myth that women should avoid Zone 2 & fasted cardio Â
47:00 â What the research *really* says about fasted training for women Â
49:00 â Fueling performance on low-carb diets: how it actually works Â
52:00 â Carbohydrate targets, CGMs & training with metabolic flexibility Â
54:00 â Stress, cortisol & how glucose spikes show up on CGMs Â
55:00 â Final thoughts & how to join Paulâs real-world nutrition study
Guest Bio:
Professor Paul Laursen is a world-leading endurance coach and exercise physiologist with 150+ peer-reviewed papers. Heâs the co-founder of Athletica.ai and author of the Human Kinetics textbook High-Intensity Interval Training. Heâs coached Olympic medalists, Ironman champions, and continues to pioneer research at the intersection of performance and health.
Resources & Links:
â Free 2-week Athletica.ai trial â https://athletica.ai Â
â Field Study: Join Athleticaâs nutrition + training research project Â
â Professor Laursenâs textbook on HIIT â https://hiitscience.com/hiit-science-book-application/
â Peter Attia: VOâmax and longevity reference â https://peterattiamd.com/all-things-vo2-max/
â Jeff Volekâs FASTER Study â Â https://pubmed.ncbi.nlm.nih.gov/26892521/
đŁ Want to thrive through menopause with evidence-based training? Enrol in Tonyâs 9-Week Course: https://scienceofthriving.com.au