Neurosalience #S6E2 with Charlotte Wiesmann - Inferring white matter connections through developmental milestones
Description
"AI is really bad at perspective taking…"
Dr. Charlotte Grosse Wiesmann is a cognitive neuroscientist exploring how the human social brain takes shape in early life. She is a Professor at the University of Technology Nuremberg and directs the Research Group on Social Brain Development at the Max Planck Institute in Leipzig. Her research blends developmental psychology, brain imaging, and computational modeling to uncover how infants begin to infer other people’s beliefs, intentions and mental states.
In this conversation, Dr. Wiesmann unpacks how children’s brains develop the capacity for social understanding and theory of mind. Drawing on developmental psychology and neuroimaging, she reveals how the brain transforms as children first succeed on false-belief tasks, a fleeting yet powerful window into the emergence of the social mind. Within this context, the conversation explores white matter maturation, environmental influences, and brain plasticity, offering fresh insights into how studying infant development can inform the future of AI. Join the conversation to discover how early brain development is reshaping our understanding of our social minds.
We hope you enjoy this episode!
Chapters:
00:00 - A Journey from Physics to Neuroscience
14:25 - Neural Bases of Early Childhood Theory of Mind
21:58 - False Belief Task and Theory of Mind
25:11 - Attention Schema for Consciousness
27:14 - Primary Areas Involved in Theory of Mind
31:24 - Impact of Neuro Deficits on Social Cognition
33:57 - Role of Environment and Timing on Social Cognition
37:11 - Implicit and Explicit Mechanisms of Social Development
45:02 - Social Cognition Across Species
47:37 - Connecting Neural Code to Social Cognition
49:56 - Temporal Progression in Theory of Mind Tasks
54:54 - Future Research Directions in Understanding Social Cognition
01:00:08 - Infant Learning Inspires AI Development
01:04:50 - Advice for Aspiring Scientists
Works mentioned:
14:31 - White matter maturation is associated with the emergence of Theory of Mind in early childhood
37:20 - Two systems for thinking about others’ thoughts in the developing brain
49:50 - Timing matters: disentangling the neurocognitive sequence of mentalizing
Episode producers:
Xuqian Michelle Li, Karthik Sama




