Bullies try to shame people by making fun of something about them.  The world tries to shame Christians these days about their faith.  People who believe in God, who believe in the truthfulness of the Bible, who believe in creation, who believe that Jesus is God in the flesh, who believe in a coming judgment day, etc. are derided and looked down upon by the world.  Jesus challenges His followers to be ready for such things, lose their lives in His service and not to be ashamed of Him or His words.  His question for us: "For what will a man give in exchange for his soul?"