This week on Pharm5:

• Novo Nordisk insulin price cuts


• Akorn Pharma closing, potential drug shortages


• Zavzpret (zavegepant) migraine nasal spray


• Daybue (trofinetide) for Rett Syndrome


• 2023 Match Results

Connect with us!

• Listen to our podcast: Pharm5


• Follow us on Twitter: @LizHearnPharmD

References:

1. Novo Nordisk to lower U.S. prices of several pre-filled insulin pens and vials up to 75% for people living with diabetes in January 2024. Novo Nordisk. http://bit.ly/42hziHz. Accessed March 16, 2023.


2. Lilly cuts insulin prices by 70% and caps patient insulin out-of-pocket costs at $35 per month. Eli Lilly and Company. https://bit.ly/3ZQXVcf. Published March 1, 2023. Accessed March 16, 2023.


3. Murphy T. Novo Nordisk plans price cuts for several insulins. AP NEWS. http://bit.ly/3JNzgjz. Published March 14, 2023. Accessed March 16, 2023.


4. Kekatos M, Bakshi N, Coburn J. Nationwide shortage of asthma medication albuterol could worsen in hospitals. ABC News. https://bit.ly/3JfD1wA. Published March 9, 2023. Accessed March 16, 2023.


5. Supply chain disruption due to manufacturer closure: Akorn Pharmaceuticals ceases operations. End Drug Shortages Alliance. https://bit.ly/3JqLZHi. Published March 7, 2023. Accessed March 16, 2023.


6. Pfizer’s Zavzpret™ (zavegepant) Migraine Nasal Spray Receives FDA Approval. Pfizer. http://bit.ly/42kQJag. Published March 10, 2023. Accessed March 16, 2023.


7. Lipton RB, Croop R, Stock DA, et al. Safety, tolerability, and efficacy of zavegepant 10 mg nasal spray for the acute treatment of migraine in the USA: A phase 3, double-blind, randomised, placebo-controlled multicentre trial. The Lancet Neurology. 2023;22(3):209-217. doi:10.1016/s1474-4422(22)00517-8


8. Sargent J, Kirchner JR, Davis R, Kirkhart B. Oral sumatriptan is effective and well tolerated for the acute treatment of migraine: results of a multicenter study. Neurology. 1995;45(8 Suppl 7):S10-S14.


9. Center for Drug Evaluation and Research. FDA approves first treatment for Rett syndrome. U.S. Food and Drug Administration. http://bit.ly/3TjSD6U. Accessed March 16, 2023.


10. Aislinn Antrim E. FDA approves Trofinetide for treatment of Rett syndrome in adult, pediatric patients. Pharmacy Times. http://bit.ly/40fK3bq. Published March 13, 2023. Accessed March 16, 2023.


11. ASHP match statistics. ASHP Match | Statistics of the Match. http://bit.ly/42e4Ga1. Published March 15, 2023. Accessed March 16, 2023.


12. Schedule of dates. ASHP Match | Schedule. https://bit.ly/3I8MJA7. Published March 15, 2023. Accessed March 16, 2023.