The Buffalo Bills are at home in Week 1 to host the Arizona Cardinals. On today's episode, Joe Marino breaks down the Bills' opponent, discusses the challenges they present and what Buffalo must do to claim a victory. Key talking points include the Buffalo Bills, Sean McDermott, Josh Allen, Dalton Kincaid, James Cook, Keon Coleman, Khalil Shakir, Ed Oliver, Von Miller, Damar Hamlin, Terrel Bernard, Rasul Douglas, Taron Johnson, Gregory Rousseau, Dion Dawkins, Arizona Cardinals, Marvin Harrison Jr., Kyler Murray, Jonathan Gannon, James Conner, Budda Baker, Week One, Preview and more!

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