Primodos: Zebrafish, GLP, and Unanswered Questions
Update: 2021-09-07
Description
Primodos, a hormone-based pregnancy test, was given to women between 1959 and 1978. Its development occurred before GLP and before standardized testing for teratogenesis (causing birth defects). There are data and suspicions that it caused birth defects, but more questions remain.
This episode of Inside Out Quality explores the story of this in vivo diagnostic with Dr. Neil Vargesson, from the University of Aberdeen, Scotland, UK. Learn another reason for the importance of Good Laboratory Practices and why pre-clinical studies are key to keeping people safe.
To learn more about Dr. Vargesson's research, visit his site here: Link
Dr. Vargesson's research publication discussed on this show: Link
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